ETHYL 2-MERCAPTOACETATE (ETHYL THIOGLYCOLATE)

ETHYL 2-MERCAPTOACETATE

PRODUCT IDENTIFICATION

CAS NO.

623-51-8

ETHYL 2-MERCAPTOACETATE

EINECS NO. 210-800-3

FORMULA HSCH₂COOC₂H₅

MOL WT. 120.17

H.S. CODE

2930.90

TOXICITY

Oral rat LD50: 178 mg/kg

SYNONYMS Ethyl Thioglycolate; Mercaptoacetic acid ethyl ester;

Ethyl mercaptoacetate; Ethyl alpha-mercaptoacetate; Ethyl mercaptoacetic acid; Thioglycolic acid ethyl ester;

SMILES

CLASSIFICATION

THIOGLYCOLATE /

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE clear liquid

MELTING POINT

BOILING POINT 157 C

SPECIFIC GRAVITY 1.1

SOLUBILITY IN WATER

VISCOSITY

AUTOIGNITION

REFRACTIVE INDEX

NFPA RATINGS

FLASH POINT 47 C

STABILITY Stable under ordinary conditions

GENERAL DESCRIPTION & APPLICATIONS

Glycolic acid is the smallest alpha-hydroxy acid (AHA) which has a hydroxyl group on the carbon atom next to the acid group. If the hydroxy group is on the second carbon next to the acid group, it is called beta-hydroxy acid. Glycolic acid is a low mole weight compound but has dual functionality of alcohol and acid. Because of its small molecular weight and size, it has a better capability to penetrate skin. AHA is used extensively in cosmetics. It is known that it diminishes the lines on the skin and make skins look young by acting as a humectant to absorb moisture in air and by exfoliating action to break the bonds between dead skin cells, Pure glycolic acid is a white crystals; decomposes about 78 C; very soluble in water, alcohols, acetone, acetates; slightly soluble in ethyl ether; sparingly soluble in hydrocarbon solvents; polymerization occurs above 50 C. Commercially, it is available in crystal form as well as in aqueous solutions of various concentrations, usually 70 percent or less. Activating both the hydroxyl and carboxylic acid group, glycolic acid has the property to form metal complexes and can be used in cleaning applications and hard water dissolution. Aqueous solution grade is mainly used fro this cleaning application. Glycolic acid is an useful intermediate in organic synthesis including oxidation/reduction, esterification and formation of oligomers as well as long chain polymerization. Glycolic acid is naturally found in sugar beets, cane sugar, and unripe grapes. It is known that it diminishes the lines on the skin and make skins look young. Synthetic glycolic acid and its derivatives are used commercially in leather tanning and textile dyeing; as a flavouring agent and preservative in food processing, water treatment industries; pH control; and chemical intermediates as well as in household, industrial, electronics cleaning applications and cosmetics. They are also used in emulsion polymers, solvents and ink and paint additive to improve flow properties and impart gloss.

'Thio' is a chemical prefix indicates the replacement of an oxygen in an acid radical by sulfur with a negative valence of 2; meaning 'sulfur' derived from the Greek theion. In substitutive nomenclature their names are formed by adding '-thiol' as a suffix to the name of the parent compound. When -SH is not the principal group, the prefix 'mercapto-' is placed before the name of the parent compound to denote an unsubstituted -SH group. Thioglycolic acid, a simple sulfur group- chained carboxylic acid, is a clear liquid; melts at -16. c, boils at 96 C; soluble in water. It is an useful chemical intermediate in the chemical reactions such as addition, elimination and cyclization. Sulfur group will react with bases, acids, ketones and organic halogen compounds, whereas the carboxylic group will preferentially react In the presence of alcohols or amines. The applications of thioglycolic acid and its derivatives are wide in the fields of;

Main materials for the synthesis of PVC stabilizers.
Down-hole acidizing
Corrosion inhibition in the oil field industry.
Manufacturing of pharmaceuticals, agrochemicals and dyes
Hair care products (waving, hair removal and hair straightening)
Shrink-resistant treatment of wool
Fabric dying
Leather processing.

Thioglycolic acid, a simple sulfur group- chained carboxylic acid, is a clear liquid; melts at -16. c, boils at 96 C; soluble in water. It is an useful chemical intermediate in the chemical reactions such as addition, elimination and cyclization. Sulfur group will react with bases, acids, ketones and organic halogen compounds, whereas the carboxylic group will preferentially react In the presence of alcohols or amines. The applications of thioglycolic acid and its derivatives are wide in the fields of PVC stabilizers, down-hole acidizing, corrosion inhibition in the oil field industry, manufacturing of pharmaceuticals, agrochemicals and dyes, shrink-resistant treatment of wool, fabric dying, leather processing.

Thioglycolates are used in cosmetic hair-care products especially permanent waving products as they weaken the keratin structure by the opening of the cystine disulfide linkages. In addition to hair-waving application, they are used as depilating agents to remove unwanted body hair. The break-down of disulfide bonds in the cortex by thioglycolates either rearranges (permanent waving) or entirely destroys (depilating) hair structure. As an antioxidant application in cosmetics, thioglycolates protect the product itself not the skin against oxidative reactions promoted by ultraviolet radiation or oxygen.

SALES SPECIFICATION

APPEARANCE

Clear liquid

ASSAY

99.0% max

SPECIFIC GRAVITY 1.10 - 1.11

TRANSPORTATION

PACKING

HAZARD CLASS 3 (Packing Group: III)

UN NO. 3071

PRICE